Strathroy-Caradoc is located approximately 35 km from London, 240 km from Toronto, 160 km from Windsor and Detroit, and 65 km from Sarnia. Strathroy-Caradoc has immediate access to Highway 402 which connects Strathroy to the major US cities. Strathroy-Caradoc is also close to Highway 401 which is a major link to the Windsor Tunnel and New York State. County Road 81 bisects Strathroy-Caradoc and connects to County Road 2 to the South and to County Road 22 and the Lake Huron Cottage Country to the North. The CN and CP Railway services Strathroy-Caradoc, running between Toronto and Chicago.